乳酸酸中毒的相关研究进展

被引:16
作者
胡宝吉 [1 ]
薄禄龙 [2 ]
邓小明 [2 ]
段宏伟 [1 ]
机构
[1] 上海市浦东医院暨复旦大学附属浦东医院麻醉科
[2] 上海长海医院麻醉科
关键词
乳酸代谢; 乳酸酸中毒; 脓毒症;
D O I
暂无
中图分类号
R459.7 [急症、急救处理];
学科分类号
100231 [临床病理学];
摘要
乳酸是体内碳水化合物和非必需氨基酸非常重要的中间代谢产物,重症患者血中乳酸浓度升高的水平对患者预后甚至病死率有着重要的警示作用。本文通过综述乳酸酸中毒的临床意义及潜在的治疗方法,阐明乳酸对机体的作用及其对疾病预后的潜在意义,为重症疾病治疗提供新的思路。
引用
收藏
页码:22 / 25
页数:4
相关论文
共 6 条
[1]
Metformin-associated lactic acidosis: Current perspectives on causes and risk [J].
DeFronzo, Ralph ;
Fleming, G. Alexander ;
Chen, Kim ;
Bicsak, Thomas A. .
METABOLISM-CLINICAL AND EXPERIMENTAL, 2016, 65 (02) :20-29
[2]
Lactic Acidosis.[J].Julie R. Ingelfinger;Jeffrey A. Kraut;Nicolaos E. Madias.The New England Journal of Medicine.2014, 24
[3]
The chemistry, physiology and pathology of pH in cancer [J].
Swietach, Pawel ;
Vaughan-Jones, Richard D. ;
Harris, Adrian L. ;
Hulikova, Alzbeta .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2014, 369 (1638)
[4]
Clinical use of lactate monitoring in critically ill patients.[J].Jan Bakker;Maarten WN Nijsten;Tim C Jansen.Annals of Intensive Care.2013, 1
[5]
Microcirculatory Alterations in Patients With Severe Sepsis: Impact of Time of Assessment and Relationship With Outcome*.[J].Daniel De Backer;Katia Donadello;Yasser Sakr;Gustavo Ospina-Tascon;Diamantino Salgado;Sabino Scolletta;Jean-Louis Vincent.Critical Care Medicine.2013, 3
[6]
Lactic acidosis during sepsis is related to increased pyruvate production, not deficits in tissue oxygen availability [J].
Gore, DC ;
Jahoor, F ;
Hibbert, JM ;
DeMaria, EJ .
ANNALS OF SURGERY, 1996, 224 (01) :97-102