补体系统与Alzheimer病(综述)

被引:1
作者
祖衡兵
陈生弟
机构
[1] 上海医科大学附属金山医院神经科!上海
[2] 上海第二医科大学附属瑞金医院神经科!上海
关键词
补体; Alzheimer病; 发病机制;
D O I
暂无
中图分类号
R749.16 [];
学科分类号
100203 ;
摘要
研究表明 ,经典补体通路的全部补体成分、多种补体调节蛋白及其受体等均在Alzheimer病 (AD)脑内存在和上调表达 ,且与含Aβ的AD病理结构密切相关。经典补体通路在AD患者脑内的活化以及活化的补体成分与AD病理损害之间的高度相关性表明 ,补体系统可能参与了AD的脑内病理活动。
引用
收藏
页码:56 / 58
页数:3
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