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苯并(a)对大弹涂鱼肝脏抗氧化防御系统影响的初步研究
被引：26
作者：
冯涛
郑微云
洪万树
余群
郑森林
张倩
机构：
[1] 厦门大学环境科学研究究中心/国家教委海洋生态环境开放研究实验室!
[2] 厦门大学海洋系!
[3] 厦门大学环境科学研究究中心
来源：
基金：
高等学校博士学科点专项科研基金;
关键词：
苯并(a)芘;
大弹涂鱼;
超氧化物歧化酶(SOD);
还原型谷胱甘肽(GSH);
丙二醛(MDA);
D O I：
暂无
中图分类号：
X50 [一般性问题];
学科分类号：
071012 ;
0713 ;
083002 ;
摘要：
Th effects of benzo(a)pyrene(BaP) on superoxide dismutase(SOD) activities, reduced glutathione(GSH) content and malondialdehyde(MDA) concentration in the liver of Boleophthalmus pectinirostris are studied in experimental condition. The results show that the activities of SOD is induced, the content of GSH increased and the concentration of MDA elevated significantly under the exposure of 30 μg/L BaP during 7 days. The overall effects are that the oxidative stress occurs under the BaP exposure, which indicates that the reactive oxygen species(ROS) have been produced in large quantities and the membrane system of the cell has been damaged. The experiment results show that it is one of the most important toxicological mechanisms of BaP that the large quantity of ROS, which induced lipid peroxidation , are generated during the metabolism of BaP in the liver of Boleophthalmus pectinirostris.
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页码：27 / 30+54
+54
页数：5
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