微生物进化工程育种技术进展与展望

被引：9

作者：

巩继贤

郑辉杰

郑宗宝

段楠

陈涛

赵学明

机构：

[1] 天津大学化工学院生物工程系系统生物学教育部重点实验室

来源：

生物加工过程 | 2010年 / 8卷 / 02期

关键词：

适应; 组合; 进化工程; 菌种改进; 选择;

D O I：

暂无

中图分类号：

Q939.9 [应用微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

进化工程是一项全基因组水平的新兴技术,它通过模拟自然进化中的变异和选择过程,实现对微生物菌株优良性状的选育。近年来,进化工程在扩大底物利用范围,提高代谢物产量及提高微生物的耐受性等方面取得了显著进展。介绍了进化工程的概念、特点及发展过程,叙述了进化工程的原理和研究方法,重点总结了进化工程方法在菌株改进方面的研究进展,最后对该技术的发展趋势和潜在应用进行了展望。

引用

页码：69 / 76

页数：8

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