银屑病瘙痒机制及治疗研究进展

被引：4

作者：

靳亚莉 ^{[1
]}

杨雪源 ^{[1
]}

王洪生 ^{[1
]}

机构：

[1] 中国医学科学院北京协和医学院皮肤病研究所

来源：

国际皮肤性病学杂志 | 2011年 / 04期

关键词：

银屑病; 瘙痒症; 细胞因子类; 治疗;

D O I：

暂无

中图分类号：

R758.63 [牛皮癣（银屑病）];

学科分类号：

100206 ;

摘要：

瘙痒是银屑病患者的一种常见症状,严重影响患者的生活质量。但其瘙痒的机制尚不清楚,许多常规治疗瘙痒的药物并不能有效缓解银屑病的瘙痒。目前认为,银屑病皮损中神经分布异常增多和敏感性增加,炎症细胞在病灶中聚集、活化并释放炎症介质是银屑病瘙痒的主要原因。抗组胺药不能有效控制银屑病瘙痒,而神经肽受体拮抗剂、免疫抑制剂及光疗等为治疗银屑病瘙痒的有效方法。

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