Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease

被引：1

作者：

Rui Guo ^{[1
]}

Emily C Liong ^{[1
]}

Kwok Fai So ^{[1
]}

ManLung Fung ^{[2
]}

George L Tipoe ^{[1
]}

机构：

[1] Departments of Anatomy Li Ka Shing Faculty of Medicine,The University of Hong Kong

[2] Physiology,Li Ka Shing Faculty of Medicine,The University of Hong Kong

来源：

Hepatobiliary & Pancreatic Diseases International | 2015年 / 14卷 / 02期

关键词：

non-alcoholic fatty liver disease; chronic aerobic exercise; oxidative stress; inflammation; apoptosis; autophagy;

D O I：

暂无

中图分类号：

R575 [肝及胆疾病];

学科分类号：

1002 ; 100201 ;

摘要：

<正>BACKGROUND:Non-alcoholic fatty liver disease(NAFLD)refers to any fatty liver disease that is not due to excessive use of alcohol.NAFLD probably results from abnormal hepatic lipid metabolism and insulin resistance.Aerobic exercise is shown to improve NAFLD.This review aimed to evaluate the molecular mechanisms involved in the beneficial effects of aerobic exercise on NAFLD.DATA SOURCE:We searched articles in English on the role of aerobic exercise in NAFLD therapy in Pub Med.

引用

页码：139 / 144

页数：6

共 21 条

[1]

Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways[J] . Jia Xiao,Chi Tat Ho,Emily C. Liong,Amin A. Nanji,Tung Ming Leung,Thomas Yue Huen Lau,Man Lung Fung,George L. Tipoe.European Journal of Nutrition . 2014 (1)

[2] Autophagic response to exercise training in skeletal muscle with age [J].

Kim, Yong An ;

Kim, Young Sang ;

Oh, Seung Lyul ;

Kim, Hee-Jae ;

Song, Wook .

JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2013, 69 (04) :697-705

[3]

Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome[J] . Derrick M. Van Rooyen,Lay T. Gan,Matthew M. Yeh,W. Geoffrey Haigh,Claire Z. Larter,George Ioannou,Narci C. Teoh,Geoffrey C. Farrell.Journal of Hepatology . 2013 (1)

[4] Increased Expression of Enzymes of Triglyceride Synthesis Is Essential for the Development of Hepatic Steatosis [J].

Jin, Jingling ;

Iakova, Polina ;

Breaux, Meghan ;

Sullivan, Emily ;

Jawanmardi, Nicole ;

Chen, Dahu ;

Jiang, Yanjun ;

Medrano, Estela M. ;

Timchenko, Nikolai A. .

CELL REPORTS, 2013, 3 (03) :831-843

[5] Treadmill exercise ameliorates apoptotic cell death in the retinas of diabetic rats [J].

Kim, Dae-Young ;

Jung, Sun-Young ;

Kim, Chang-Ju ;

Sung, Yun-Hee ;

Kim, Jae-Deung .

MOLECULAR MEDICINE REPORTS, 2013, 7 (06) :1745-1750

[6]

Supplementation with a juice powder concentrate and exercise decrease oxidation and inflammation, and improve the microcirculation in obese women: randomised controlled trial data[J] . Manfred Lamprecht,Georg Obermayer,Kurt Steinbauer,Gerhard Cvirn,Lidija Hofmann,Gerhard Ledinski,Joachim F. Greilberger,Seth Hallstroem.British Journal of Nutrition . 2013 (9)

[7]

Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats[J] . Li Luo,A-Ming Lu,Yan Wang,An Hong,Yulan Chen,Juan Hu,Xiaoning Li,Zheng-Hong Qin.Experimental Gerontology . 2013 (4)

[8] Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model [J].

Xiao, Jia ;

Ching, Yick Pang ;

Liong, Emily C. ;

Nanji, Amin A. ;

Fung, Man Lung ;

Tipoe, George L. .

EUROPEAN JOURNAL OF NUTRITION, 2013, 52 (01) :179-191

[9]

Moderate Exercise Training Induces ROS-Related Adaptations to Skeletal Muscles[J] . P. Abruzzo,F. Esposito,C. Marchionni,S. di Tullio,S. Belia,S. Fulle,A. Veicsteinas,M. Marini.Int J Sports Med . 2013

[10]

Autophagy, signaling and obesity[J] . Vanessa J. Lavallard,Alfred J. Meijer,Patrice Codogno,Philippe Gual.Pharmacological Research . 2012 (6)

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