多西他赛联合顺铂、5-Fu治疗晚期胃癌近期疗效分析

被引:12
作者
陈绍水
宁方玲
吕俊华
赵磊
于泽顺
彭宪忠
机构
[1] 山东省滨州医学院附属医院肿瘤科
关键词
胃癌; 多西他赛; 顺铂; 氟尿嘧啶; 药物治疗;
D O I
暂无
中图分类号
R735.2 [胃肿瘤];
学科分类号
摘要
目的观察多西他赛联合顺铂、5-Fu治疗晚期胃癌的疗效及耐受性。方法TDF方案:Docetaxel75mg/m2静脉滴注,第1天,化疗前预处理;顺铂20mg,静脉滴注,第1~5天;5-Fu2.5g/m2持续静脉灌注120小时,21天为1周期。结果全组CR1例、PR12例、SD9例、PD1例,总有效率56.5%。初治组有效率70%,复治组有效率46%。中位生存期为13月。不良反应主要有消化道反应和白细胞下降。结论TDF方案疗效肯定,不良反应能耐受。
引用
收藏
页码:658 / 659
页数:2
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