脉冲射频治疗外周神经病理性疼痛模型的研究进展

被引：19

作者：

贾子普

罗芳

机构：

[1] 首都医科大学附属北京天坛医院疼痛中心

来源：

中国疼痛医学杂志 | 2015年 / 21卷 / 04期

关键词：

脉冲射频; 神经病理性疼痛; 实验研究;

D O I：

暂无

中图分类号：

R745 [周围神经及神经节疾病];

学科分类号：

100204 [神经病学];

摘要：

近年来,脉冲射频作为一种新颖的疼痛介入治疗技术广泛应用于神经病理性疼痛的临床治疗,但其作用机制尚不清楚。神经病理性疼痛按照神经损伤的部位可以分为中枢和外周两大类。目前,国内外实验研究报道脉冲射频治疗多种外周神经病理性疼痛模型取得了确切的疗效,其机制可能涉及脉冲射频抑制脊髓背角小胶质细胞的活化、影响细胞因子的表达、痛觉纤维的传导及离子通道的表达等。然而,脉冲射频治疗疼痛确切的机制尚待深入的实验研究加以明确。

引用

页码：293 / 296

页数：4

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