胆红素与心血管疾病

被引:20
作者
沈定树
边藏历
机构
[1] 浙江省台州医院
[2] 湖北省职工医学院
关键词
胆红素; 抗氧化剂; 血红素氧化酶; 心血管疾病;
D O I
暂无
中图分类号
R54 [心脏、血管(循环系)疾病];
学科分类号
摘要
胆红素是一种生理性抗氧化剂 ,其活性受胆红素氧化酶 (HO)的影响。HO有三种异构体 ,HO 1是诱导式 ,HO 2和HO 3是构造式 ,在细胞抗氧化防御机理中HO 1有重要作用。胆红素的抗氧化性质是使脂链断裂 ,阻止低密度脂蛋白的氧化 ,因此 ,血清高浓度胆红素可以减少动脉粥样硬化形成的危险性 ,而低浓度则可增加其发病率。
引用
收藏
页码:329 / 330
页数:2
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