促肾上腺皮质激素释放因子与肠易激综合征

被引：10

作者：

常敏

方秀才

机构：

[1] 中国医学科学院北京协和医学院北京协和医院消化内科

来源：

基础医学与临床 | 2011年 / 31卷 / 12期

关键词：

肠易激综合征; 促肾上腺皮质激素释放因子; 应激;

D O I：

10.16352/j.issn.1001-6325.2011.12.013

中图分类号：

R574.4 [肠道功能紊乱];

学科分类号：

1002 ; 100201 ;

摘要：

肠易激综合征(IBS)是一种个体特异性、多病因的异质性疾病,其发病和患者的精神状态、社会环境、生活应激等多种心理社会因素密切相关。促肾上腺皮质激素释放因子(CRF)是一种介导下丘脑-垂体-肾上腺(HPA)轴对应激反应的关键调节肽,参与脑-肠轴互动,通过影响胃肠道动力、内脏高敏感和肠道感染等参与IBS的发病。

引用

页码：1396 / 1399

页数：4

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