C-反应蛋白在动脉粥样硬化中的作用

被引:29
作者
潘清蓉
孙梅励
机构
[1] 中国医学科学院中国协和医科大学北京协和医院内分泌科
[2] 中国医学科学院中国协和医科大学北京协和医院内分泌科 北京
[3] 北京
关键词
C-反应蛋白; 动脉粥样硬化; 心血管疾病;
D O I
暂无
中图分类号
R543 [血管疾病];
学科分类号
1002 ; 100201 ;
摘要
C 反应蛋白 (C reactiveprotein ,CRP)是反映炎症的敏感指标。近年的研究揭示超敏C 反应蛋白 (high sensitiveCRP ,hs CRP)是心血管疾病的危险标志之一。同时还发现CRP自身可能直接参与了动脉粥样硬化的过程 ,CRP可增加单核细胞向血管壁黏附、促进巨噬细胞摄取LDL、促使内皮细胞功能失调及促进平滑肌细胞迁移和增生 ;CRP还与血栓形成和斑块的破裂有关。
引用
收藏
页码:462 / 465
页数:4
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