血管内皮生长因子及其受体对缺血性脑血管病脑微血管生成作用机制研究进展

被引：18

作者：

刘轲

杨歆科

李建生

机构：

[1] 河南中医学院第一附属医院

来源：

国外医学(老年医学分册) | 2009年 / 30卷 / 01期

关键词：

血管内皮生长因子; 血管内皮生长因子受体; 缺血性脑血管病; 血管生成;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

100204 [神经病学];

摘要：

血管内皮生长因子及其受体具有促进内皮细胞增殖,加速新生血管形成,增加血管通透性等特点,它与缺血性脑血管病的发生发展密切相关。本文将从血管内皮生长因子及其受体的概况、诱导途径、在脑缺血损伤后血管生成中的利弊影响几方面对血管内皮生长因子/血管内皮生长因子受体系统作一综述,详述其在血管生成方面的调控机制、时空表达、细胞分布及剂量关系等特点,并对血管内皮生长因子在目前应用中遇到的问题及在未来临床中的应用前景予以分析。

引用

页码：23 / 29

页数：7

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