生长激素对免疫细胞功能调节的研究进展

被引:9
作者
王辉
邓洁英
史轶蘩
机构
[1] 新乡医学院免疫学教研室
[2] 中国医学科学院!中国协和医科大学
[3] 北京协和医院
[4] 北京
关键词
生长激素; 胸腺细胞; 淋巴细胞;
D O I
暂无
中图分类号
R392.13 [免疫分子遗传学];
学科分类号
摘要
目前研究表明 ,生长激素 (GH)在体内和体外能促进胸腺基质细胞 (TEC)分泌胸腺素 ,并且能增强细胞外基质介导的TEC与胸腺细胞的相互作用 ;在体外GH能促进植物血凝素刺激的正常人T淋巴细胞的增殖 ,GH能增加外周血分泌γ干扰素 (IFN γ)单个核细胞的数量及IFN γ分泌的量 ;GH可直接或间接影响B细胞的发育和功能 ;GH缺乏的儿童和成人的自然杀伤 (NK)细胞数量正常 ,但活性降低 ,而补充GH后NK细胞活性增加 ;GH能增强佛波酯刺激单核细胞的一氧化氮产生。
引用
收藏
页码:91 / 94
页数:4
相关论文
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