帕金森病患者反应抑制功能损害及其事件相关电位变化

被引：1

作者：

李艳敏 ^{[1
,2
]}

王琳 ^{[1
]}

王铭维 ^{[1
,2
]}

机构：

[1] 河北医科大学第一医院神经内科

[2] 河北省脑老化与认知神经科学实验室

来源：

中华物理医学与康复杂志 | 2012年 / 09期

关键词：

D O I：

暂无

中图分类号：

R742.5 [震颤麻痹综合征];

学科分类号：

1002 ;

摘要：

<正>随着神经解剖学、神经生物学和临床检测手段的发展与进步,有关帕金森病(Parkinson's disease,PD)的研究越来越多。PD不仅仅是一种单纯的运动障碍病,它还会影响到患者的认知功能、精神行为、自主神经功能及感觉系统。近年来,PD所导致的认知功能障碍引起了较多学者的关注。有研究发现,超过80%的PD患者会出现认知功能改变,约30%的患者最终会进展为帕金森病痴呆(Parkinson's diseasedementia,PDD),严重影响到患者的生活质量及治疗效果。PD

引用

页码：708 / 711

共 14 条

[1] 轻度认知功能障碍患者视觉注意的事件相关电位研究 [J].

王烁 ;

李秀艳 ;

苏萌萌 ;

孟庆慧 ;

张媛媛 ;

孙淑凤 .

中华物理医学与康复杂志, 2011, (05) :345-349

[2] Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson's disease [J].

Benabid, Alim Louis ;

Chabardes, Stephan ;

Mitrofanis, John ;

Pollak, Pierre .

LANCET NEUROLOGY, 2009, 8 (01) :67-81

[3] Response inhibition in Huntington's disease - A study using ERPs and sLORETA [J].

Beste, Christian ;

Saft, Carsten ;

Andrich, Juergen ;

Gold, Ralf ;

Falkenstein, Michael .

NEUROPSYCHOLOGIA, 2008, 46 (05) :1290-1297

[4]

Response Inhibition and Response Selection: Two Sides of the Same Coin[J] . Stewart H. Mostofsky,Daniel J. Simmonds.Journal of Cognitive Neuroscience . 2008 (5)

[5] Activation of right inferior frontal gyrus during response inhibition across response modalities [J].

Chikazoe, Junichi ;

Konishi, Seiki ;

Asari, Tomoki ;

Jimura, Koji ;

Miyashita, Yasushi .

JOURNAL OF COGNITIVE NEUROSCIENCE, 2007, 19 (01) :69-80

[6]

Functions of frontostriatal systems in cognition: Comparative neuropsychopharmacological studies in rats, monkeys and humans[J] . Y. Chudasama,T.W. Robbins.Biological Psychology . 2006 (1)

[7]

Information processing, dimensionality reduction and reinforcement learning in the basal ganglia[J] . Izhar Bar-Gad,Genela Morris,Hagai Bergman.Progress in Neurobiology . 2003 (6)

[8] Electrophysiological correlates for response inhibition in a Go/NoGo task [J].

Bokura, H ;

Yamaguchi, S ;

Kobayashi, S .

CLINICAL NEUROPHYSIOLOGY, 2001, 112 (12) :2224-2232

[9] Executive frontal functions [J].

Fuster, JM .

EXPERIMENTAL BRAIN RESEARCH, 2000, 133 (01) :66-70

[10]

Inhibitory control in children with attention-deficit/hyperactivity disorder: event-related potentials identify the processing component and timing of an impaired right-frontal response-inhibition mechanism[J] . Steven R Pliszka,Mario Liotti,Marty G Woldorff.Biological Psychiatry . 2000 (3)

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