应用FRAX筛查骨质疏松高危人群的方法研究

被引:10
作者
唐松涛 [1 ]
刘安银 [2 ]
章秋 [1 ]
沈馨茹 [1 ]
机构
[1] 安徽医科大学第一附属医院内分泌科
[2] 合肥工业大学校医院
关键词
骨质疏松性骨折; 危险因子; 骨密度; 骨折风险性; FRAX;
D O I
暂无
中图分类号
R580 [];
学科分类号
摘要
目的应用骨折风险评估工具(FRAX)预测不同骨质疏松性骨折危险因子及股骨颈骨密度(BMD)情况下10年骨折风险性的差异,探讨筛查骨质疏松高危人群的方法。方法应用FRAX的中国大陆子模型软件,综合年龄、性别、体重指数,计算单一危险因子或多重危险因子在联合或不联合BMD的条件下预测骨折风险性。结果随着BMD下降、骨折危险因子增多,10年骨质疏松性骨折风险增大。不同骨折危险因子和BMD配对时骨折风险性不同,当BMD未达骨质疏松诊断标准而合并部分危险因子时的骨折风险性大于BMD的T值达-2.5SD但无危险因子时的骨折风险性。结论 FRAX模型使原来单凭BMD转向综合各类危险因子评估长期骨质疏松性骨折风险性,在无条件行BMD检测地区可用以筛查骨质疏松高危人群。
引用
收藏
页码:984 / 988
页数:5
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