以多发磨玻璃影为表现肺癌的评价和处理

被引:3
作者
邱小玲
徐燕
王孟昭
机构
[1] 中国医学科学院北京协和医院
关键词
肺肿瘤; 磨玻璃结节; 多原发癌; 诊断; 治疗;
D O I
暂无
中图分类号
R734.2 [肺肿瘤];
学科分类号
100117 [系统生物医学];
摘要
近年来,肺部磨玻璃影(ground-glass opacity,GGO)逐渐得到临床医生关注,GGO多数情况下呈惰性,但也可进一步发展为肺癌。肺多发GGO肺癌大部分为多原发癌(multiple primary lung cancer,MPLC),不是肺内转移癌。对于怀疑为多发GGO肺癌,治疗方式主要为手术切除,同时获得病理诊断,通过不同病灶的驱动基因检测最终明确多原发癌的诊断。手术方式可以选择亚肺叶切除或楔形切除最主要的病灶。研究表明最主要病灶的直径和病灶类型与预后明显相关,而遗留的GGO病灶是否长大、是否出现新的GGO病灶、是否所有的GGO病灶被处理对患者的预后影响小。该文旨在正确评价和处理肺多发GGO肺癌。
引用
收藏
页码:540 / 543
页数:4
相关论文
共 10 条
[1]
Novel Strategy for Synchronous Multiple Primary Lung Cancer Displaying Unique Molecular Profiles [J].
Ye, Chenyang ;
Wang, Ji ;
Li, Wenshan ;
Chai, Ying .
ANNALS OF THORACIC SURGERY, 2016, 101 (02) :E45-E47
[2]
Pulmonary Metastases from NSCLC and MPLC (Multiple Primary Lung Cancers): Management and Outcome in a Single Centre Experience [J].
Stella, Franco ;
Luciano, Giulia ;
Dell'Amore, Andrea ;
Greco, Domenico ;
Ammari, Chadi ;
Giunta, Domenica ;
Bini, Alessandro .
HEART LUNG AND CIRCULATION, 2016, 25 (02) :191-195
[3]
Survival of a surgical series of lung cancer patients with synchronous multiple ground-glass opacities, and the management of their residual lesions [J].
Shimada, Yoshihisa ;
Saji, Hisashi ;
Otani, Keishi ;
Maehara, Sachio ;
Maeda, Junichi ;
Yoshida, Koichi ;
Kato, Yasufumi ;
Hagiwara, Masaru ;
Kakihana, Masatoshi ;
Kajiwara, Naohiro ;
Ohira, Tatsuo ;
Akata, Soichi ;
Ikeda, Norihiko .
LUNG CANCER, 2015, 88 (02) :174-180
[4]
Long-Term Outcomes of Wedge Resection for Pulmonary Ground-Glass Opacity Nodules [J].
Cho, Jong Ho ;
Choi, Yong Soo ;
Kim, Jhingook ;
Kim, Hong Kwan ;
Zo, Jae Ill ;
Shim, Young Mog .
ANNALS OF THORACIC SURGERY, 2015, 99 (01) :218-223
[5]
Changes in Pulmonary Function in Lung Cancer Patients After Video-Assisted Thoracic Surgery [J].
Kim, Se Joong ;
Lee, Yeon Joo ;
Park, Jong Sun ;
Cho, Young-Jae ;
Cho, Sukki ;
Yoon, Ho Il ;
Kim, Kwhanmien ;
Lee, Jae Ho ;
Jheon, Sanghoon ;
Lee, Choon-Taek .
ANNALS OF THORACIC SURGERY, 2015, 99 (01) :210-217
[6]
The association between baseline clinical–radiological characteristics and growth of pulmonary nodules with ground-glass opacity.[J].Yoshihisa Kobayashi;Yukinori Sakao;Gautam A. Deshpande;Takayuki Fukui;Tetsuya Mizuno;Hiroaki Kuroda;Noriaki Sakakura;Noriyasu Usami;Yasushi Yatabe;Tetsuya Mitsudomi.Lung Cancer.2014, 1
[7]
Safe and Effective Minimally Invasive Approaches for Small Ground Glass Opacity [J].
Kohno, Tadasu ;
Fujimori, Sakashi ;
Kishi, Kazuma ;
Fujii, Takeshi .
ANNALS OF THORACIC SURGERY, 2010, 89 (06) :S2114-S2117
[8]
Management of Multiple Pure Ground-Glass Opacity Lesions in Patients with Bronchioloalveolar Carcinoma [J].
Kim, Hong Kwan ;
Choi, Yong Soo ;
Kim, Jhingook ;
Shim, Young Mog ;
Lee, Kyung Soo ;
Kim, Kwhanmien .
JOURNAL OF THORACIC ONCOLOGY, 2010, 5 (02) :206-210
[9]
Comprehensive Histologic Assessment Helps to Differentiate Multiple Lung Primary Nonsmall Cell Carcinomas From Metastases [J].
Girard, Nicolas ;
Deshpande, Charuhas ;
Lau, Christopher ;
Finley, David ;
Rusch, Valerie ;
Pao, William ;
Travis, William D. .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2009, 33 (12) :1752-1764
[10]
Epidermal Growth Factor Receptor Mutation and Pathologic-Radiologic Correlation Between Multiple Lung Nodules with Ground-Glass Opacity Differentiates Multicentric Origin from Intrapulmonary Spread [J].
Chung, Jin-Haeng ;
Choe, Gheeyoung ;
Jheon, Sanghoon ;
Sung, Sook-Whan ;
Kim, Tae Jung ;
Lee, Kyung Won ;
Lee, Jae Ho ;
Lee, Choon-Taek .
JOURNAL OF THORACIC ONCOLOGY, 2009, 4 (12) :1490-1495