宏基因组测序在感染性疾病病原体检测中的应用

被引:29
作者
李林海
陈丽丹
肖斌
孙朝晖
机构
[1] 解放军广州总医院检验科
关键词
高通量测序; 宏基因组测序; 感染性疾病; 病原体;
D O I
暂无
中图分类号
R440 []; R51 [传染病];
学科分类号
100401 ;
摘要
感染性疾病的致病因素复杂,临床表现多样。快速、全面、准确地鉴别病原体,是临床医生及时、有针对性地采取治疗措施的前提。传统的病原体检测方法目标单一、耗时长、操作复杂,很难满足当今感染性疾病诊治的要求。宏基因组测序技术克服了多数病原体不能培养的弊端,能够准确高效地获得全部病原体遗传物质信息,直接检测出感染性疾病的病原体,对疑难感染性疾病的诊断具有重要参考价值。本文对宏基因组测序在感染性疾病病原体检测中的最新研究进展和应用进行综述。
引用
收藏
页码:15 / 18
页数:4
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