脓毒血症与急性肾损伤

被引:7
作者
鲁灵
张玲
机构
[1] 重庆医科大学附属第二医院肾内科
关键词
脓毒血症; AKI; 肾功能; 肾损伤; 肾血流量;
D O I
暂无
中图分类号
R459.7 [急症、急救处理]; R692 [肾疾病];
学科分类号
100218 ;
摘要
<正>脓毒血症是机体被致病菌感染,细菌释放毒素(主要为革兰阴性菌脂多糖)进入血液循环,激活内皮细胞等机体防御系统,释放大量细胞因子、血小板活化因子、内皮素、花生四烯酸代谢产物、补体成分等进入全身血液循环,细菌毒素的直接损伤和机体过度防御机制共同作用,引发的全身炎症反应综合症。
引用
收藏
页码:3652 / 3654
页数:3
相关论文
共 7 条
  • [1] 血必净注射液对脓毒血症患者的肾保护作用
    潘娅静
    徐建国
    徐敏
    赵洁
    [J]. 实用医学杂志, 2009, 25 (20) : 3472 - 3473
  • [2] Pathophysiology of septic acute kidney injury: What do we really know?[J] . Li Wan,Sean M. Bagshaw,Christoph Langenberg,Takao Saotome,Clive May,Rinaldo Bellomo.Critical Care Medicine . 2008 (4 Su)
  • [3] Oliguria, volume overload, and loop diuretics[J] . Sean M. Bagshaw,Rinaldo Bellomo,John A. Kellum.Critical Care Medicine . 2008 (4 Su)
  • [4] The balance of angiotensin II and nitric oxide in kidney diseases
    Singh, Prabhleen
    Deng, Aihua
    Weir, Matthew R.
    Blantz, Roland C.
    [J]. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2008, 17 (01) : 51 - 56
  • [5] A systematic review of urinary findings in experimental septic acute renal failure
    Bagshaw, Sean M.
    Langenberg, Christoph
    Wan, Li
    May, Clive N.
    Bellomo, Rinaldo
    [J]. CRITICAL CARE MEDICINE, 2007, 35 (06) : 1592 - 1598
  • [6] Sepsis and the kidney
    Klenzak, J
    Himmelfarb, J
    [J]. CRITICAL CARE CLINICS, 2005, 21 (02) : 211 - +
  • [7] Endotoxemic renal failure in mice:role of tumor necrosis factor independent of inducible nitric oxide synthase. Knotek M,Rogachev B,Wang W,et al. Kidney International . 2007