孕中期母血清生化指标的异常和不良妊娠结局关系的临床研究

被引:11
作者
李光辉
黄醒华
机构
[1] 首都医科大学附属北京妇产医院!北京
关键词
甲胎蛋白类; 促性腺激素类.绒毛膜; 妊娠特异性β1糖蛋白; 妊娠中期; 妊娠结局;
D O I
暂无
中图分类号
R715.3 [孕期卫生与保健];
学科分类号
1004 ;
摘要
目的探讨孕中期血清生化指标异常与不良妊娠结局的关系。方法在孕中期对AFP、hCG及SP1等五项血清生化指标进行测定,采用群组研究方法。结果孕中期AFP、hCG及SP1的异常升高或降低是早产、IUGR及先兆子痫等不良妊娠结局的危险因素;联合筛查可提高阳性检出率。结论孕中期血清生化指标的筛查有可能成为预测不良妊娠结局的主要手段。
引用
收藏
页码:134 / 137
页数:4
相关论文
共 9 条
[1]  
Elevated secondtrimester human chorionic gonadotrogin levels in associationwith poor pregnancy outcome. Wenstrom KD,Owen J,Boots LR,et al. American Journal of Obstetrics and Gynecology . 1994
[2]  
Elevated second trimester maternal serum hCG alone or in combination with elevated alpha-feto-protein. Benn PA,Home,Brigarti S. Obstetrics and Gynecology . 1996
[3]  
Concentration ofPregnancy sPecific β1 glygoprotein in maternal blood in normalpregnancy and in intrauterine retardation. Gordon YP,Grudzinskas JG,Jeffrey D,et al. The Lancet . 1977
[4]  
Association between perinatal outcome and serially obstained second.andthird-trimester maternal serum a-fetoprotein measurements. Simpson JL,Palomaki GE,Mercer B,et al. American Journal of Obstetrics and Gynecology . 1995
[5]  
Circulation levels ofvresnancy-specific β1 glycoprotein in normal and nathologicalpregnancies. Majumdar S,Dahiya R,Mapa MK,et al. Indian Journal of Medical Research . 1984
[6]  
Unexplained elevated maternal serum alpha-fetoprotein In singleton pregnancies as a predictor of fetal risk. Akinbiyi AA. JObstet Gynecol . 1996
[7]  
Elevated maternalserum alpha-fetopreotein: association with placental sonolucencies,fetomaternal bemorrhage, vaginal bleeding,and pregnancy outcome in the absence of fetal anormalies. Bernstein IM,Barth RA,Miller R,et al. Obstetrics and Gynecology . 1992
[8]  
Effect of hypoxia on trophoblast In organ culture a morphologic and autoradiographic study. Fox H. American Journal of Obstetrics and Gynecology . 1970
[9]  
Elevated second trimester humanchorionic gonadotropin level associated with adverse pregnancyoutcome. nderoglu LS,Kabukcu A. J Obstet Gynecol . 1997