中东呼吸综合征的临床治疗和小分子治疗药物研究进展

被引：4

作者：

李行舟

周辛波

钟武

机构：

[1] 国家应急防控药物工程技术研究中心,军事医学科学院毒物药物研究所

来源：

国际药学研究杂志 | 2015年 / 42卷 / 03期

关键词：

中东呼吸综合征; 中东呼吸综合征冠状病毒; 抗病毒药物; 临床治疗;

D O I：

10.13220/j.cnki.jipr.2015.03.002

中图分类号：

R511 [病毒传染病];

学科分类号：

摘要：

中东呼吸综合征(MERS)是由新型冠状病毒MERS-CoV感染引起的传染病,2012年在沙特被首次发现,疫情主要集中在中东地区,在欧洲、非洲、北美洲和亚洲也有少量病例报告,近期韩国连续报告数十病例,并且1例经香港输入中国大陆地区。目前,临床上尚无针对MERS-CoV的特异性抗病毒药物和治疗方法,主要是对症治疗,在防止并发症的同时实施有效的呼吸、循环支持和肾功能保护。本文对文献报道的潜在临床治疗方法,抗MERS-CoV的潜在药物靶点和小分子治疗药物的研究进展进行综述。

引用

页码：296 / 302

页数：7

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