儿童脑干胶质瘤生存时间的相关因素分析

被引：2

作者：

孙涛

万伟庆

吴震

张俊廷

张力伟

机构：

[1] 首都医科大学附属北京天坛医院神经外科

来源：

中国微侵袭神经外科杂志 | 2012年 / 17卷 / 02期

关键词：

神经胶质瘤; 脑干; 局限型; 弥漫型; 生存时间; 儿童;

D O I：

暂无

中图分类号：

R739.41 [颅内肿瘤及脑肿瘤];

学科分类号：

100115 [医学神经生物学];

摘要：

目的探讨影响儿童脑干胶质瘤生存时间的相关因素。方法回顾性分析33例儿童脑干胶质瘤病人的临床资料。应用Kaplan-Meier法进行单因素分析,分析临床、影像和病理组织学因素对生存时间的影响。差异的显著性检验应用Log-rank法,对单因素分析中P<0.05者进行COX回归多因素模型分析。结果单因素分析显示影响生存时间的因素包括:发病年龄、发病到就诊时间、入院时KPS评分、肿瘤部位、病理级别、肿瘤生长类型以及治疗方法(均P<0.05)。多因素分析显示:病人的发病到就诊时间(P=0.034)及肿瘤生长类型(P=0.046)对生存时间的影响更为显著。结论儿童脑干胶质瘤的生存时间与多种因素有关,手术切除可延长生存时间。

引用

页码：63 / 66

页数：4

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