高血压患者血浆同型半胱氨酸与年龄、性别、尿酸及血脂的相关性分析

被引:22
作者
张涛
吕纯芳
刘琨
李丽玲
佟立峰
雷顺俊
卢留珠
机构
[1] 深圳市南山区慢性病防治院
关键词
高血压; 年龄; 性别; 同型半胱氨酸; 尿酸; 血脂; 多元回归分析;
D O I
暂无
中图分类号
R544.1 [高血压];
学科分类号
1002 ; 100201 ;
摘要
目的对高血压患者的血浆同型半胱氨酸(Hcy)与年龄(Age)、性别(Sex)、血脂及血浆尿酸(UA)的相关性进行分析研究。方法依托社区综合防治项目,采用生化酶法对2 350名高血压患者,其中男1 190人,女1 160人,进行血浆同型半胱氨酸、尿酸(UA)、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)检测,并采用多元回归方法进行相关性分析。结果统计显示年龄、性别和尿酸对Hcy的影响差异有统计学意义,而TC、TG和LDL对Hcy无影响。年龄每增加1岁,log(Hcy)平均增加0.0055μmol/L;和男性相比,女性log(Hcy)平均低0.324μmol/L;UA每增加1μmol/L,log(Hcy)增加0.0005μmol/L。结论一定范围内,同型半胱氨酸与尿酸呈正相关,与TC、TG和LDL未发现明显相关。
引用
收藏
页码:786 / 788
页数:3
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