脓毒症的免疫抑制

被引：5

作者：

许煊

王猛

机构：

[1] 北京,中国人民解放军陆军总医院附属八一儿童医院儿童重症医学科

来源：

国际儿科学杂志 | 2018年 / 45卷 / 11期

关键词：

脓毒症; 免疫麻痹; 免疫抑制; 免疫治疗;

D O I：

暂无

中图分类号：

R720.597 [儿科急症及处理];

学科分类号：

100202 [儿科学];

摘要：

脓毒症是多种炎性因子影响免疫功能而导致的感染性疾病, 是ICU患者主要的死亡原因。脓毒症作为一种由不可控炎症引起的综合征, 包含大量且持续的炎症反应以及长期的免疫抑制状态, 这会增加脓毒症患者继发院内感染的发生率。脓毒症患者的免疫状态会随着病程发展不断变化, 不同的生物标志物有助于识别患者所处的免疫阶段。免疫增强治疗有望降低免疫麻痹的脓毒症患者的病死率。

引用

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