老年脑梗死病人血脂与颈动脉粥样硬化斑块超声特征及相关性研究

被引：6

作者：

马洁

机构：

[1] 西安交通大学医学院附属红会医院内科

来源：

中国实用神经疾病杂志 | 2014年 / 17卷 / 21期

关键词：

老年脑梗死; 血脂; 颈动脉粥样硬化; 斑块;

D O I：

暂无

中图分类号：

R743.33 [脑栓塞];

学科分类号：

摘要：

目的分析并评价老年脑梗死病人颈动脉粥样硬化斑块超声与血脂指标之间的相关性。方法将我院自2010-03—2012-04收治的420例老年脑梗死住院病人作为观察组,另将我院同期住院的420例非脑梗死病人作为对照组,比较2组血脂指标;同时按超声检查结果,将420例脑梗死病人根据颈动脉是否存在斑块情况分成有斑块组(306例)与无斑块组(114例),分析颈动脉粥样硬化斑块发生与各血脂指标之间的相关性。结果观察组颈动脉斑块检出率为76.9%(323例),对照组检出率为18.1%(76例),观察组明显高于对照组,差异有统计学意义(χ2=11.452,P<0.01)。观察组血清中TG、TC、apoB、LDL-C及LPa水平明显高于对照组(t=7.451,9.043,7.054,6.953,7.439,P<0.01或<0.05),而血清中HDL-C及apoA水平显著低于对照组,差异有统计学意义(t=8.151,8.042,P<0.05)。观察组中颈动脉有斑块组血清中TG、LDL-C、Lpa以及apoB含量明显高于无斑块组,血清中LDL-C及LPa含量与颈动脉粥样硬化间呈正相关(P<0.05)。结论LDL-C与LPα水平升高是诊断颈动脉粥样硬化斑块形成的主要指标,超声联合血脂检测对颈动脉粥样硬化斑块形成的早期诊断、指导治疗及预防具有重要参考价值。

引用

页码：80 / 81

页数：2

共 8 条

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