老年高血压患者动脉僵硬度的影响因素

被引：43

作者：

方向阳

吴金玲

牛红育

陆玫

刘淼冰

机构：

[1] 首都医科大学附属北京朝阳医院综合科

来源：

中华高血压杂志 | 2009年 / 17卷 / 08期

关键词：

老年; 高血压; 动脉僵硬度;

D O I：

10.16439/j.cnki.1673-7245.2009.08.003

中图分类号：

R544.1 [高血压];

学科分类号：

1002 ; 100201 ;

摘要：

目的探讨老年高血压患者动脉僵硬度的相关因素。方法选择老年高血压患者119例,平均年龄(75.6±7.0)岁,测定颈股动脉脉搏波传导速度(cfPWV)作为评价动脉僵硬度指标,以cfPWV>12m/s为标准,把所有患者分为2组,cfPWV>12m/s组,共70例,cfPWV≤12m/s组,共49例,患者行颈动脉超声检查评价颈动脉粥样斑块情况,并测量血压、糖化血红蛋白等指标,以cfPWV>12m/s为因变量,以颈动脉粥样斑块、血压、糖化血红蛋白等指标为自变量,行多因素Logistic回归分析。结果校正了体质量指数、性别、脑卒中、空腹血糖等因素后,影响cfPWV的因素有年龄、收缩压、脉压、冠心病、糖尿病、颈动脉粥样斑块、糖化血红蛋白,其中以年龄与收缩压危险度最大。结论老年高血压患者动脉僵硬度与年龄、收缩压、脉压、冠心病、糖尿病、颈动脉粥样斑块、糖化血红蛋白密切相关,其中以年龄与收缩压危险度最大。

引用

页码：716 / 719

页数：4

共 9 条

[1] 高血压病患者脉搏波速度与心血管疾病危险因素 [J].

谭静 ;

华琦 ;

闻静 ;

邢绣荣 .

中华高血压杂志, 2007, (10) :807-811

[2] 不同动脉弹性功能参数的相关性 [J].

蔡凯愉 ;

张维忠 ;

邱惠丽 .

中华高血压杂志, 2006, (11) :870-873

[3]

Assessment of Aortic Pulse Wave Velocity and Cardiac Diastolic Function in Subjects With and Without the Metabolic Syndrome: HDL cholesterol is independently associated with cardiovascular function[J] . Roes, Stijntje D,Dehnavi, Reza Alizadeh,Westenberg, Jos J M,Lamb, Hildo J,Mertens, Bart J A,Tamsma, Jouke T,de Roos, Albert.Diabetes Care . 2008 (7)

[4]

Aortic Diameter, Wall Stiffness, and Wave Reflection in Systolic Hypertension[J] . Gary F. Mitchell,Paul R. Conlin,Mark E. Dunlap,Yves Lacourcière,J Malcolm O. Arnold,Richard I. Ogilvie,Joel Neutel,Joseph L. Izzo,Marc A. Pfeffer.Hypertension . 2008 (1)

[5] Relationship of fibrinogen with arterial stiffness and wave reflections [J].

Vlachopoulos, Charalambos ;

Pietri, Panagiota ;

Aznaouridis, Konstantinos ;

Vyssoulis, Gregory ;

Vasiliadou, Carmen ;

Bratsas, Athanasios ;

Tousoulis, Dimitris ;

Xaplanteris, Panagiotis ;

Stefanadi, Elli ;

Stefanadis, Christodoulos .

JOURNAL OF HYPERTENSION, 2007, 25 (10) :2110-2116

[6]

Elevated Aortic Pulse Wave Velocity, a Marker of Arterial Stiffness, Predicts Cardiovascular Events in Well-Functioning Older Adults[J] . Kim Sutton-Tyrrell,Samer S. Najjar,Robert M. Boudreau,Lakshmi Venkitachalam,Varant Kupelian,Eleanor M. Simonsick,Richard Havlik,Edward G Lakatta,Harold Spurgeon,Stephen Kritchevsky,Marco Pahor,Douglas Bauer,Anne Newman.Circulation . 2005 (25)

[7]

Increased Central Artery Stiffness in Impaired Glucose Metabolism and Type 2 Diabetes: The Hoorn Study[J] . Miranda T. Schram,Ronald M.A Henry,Rob A.J.M van Dijk,Piet J. Kostense,Jacqueline M. Dekker,Giel Nijpels,Robert J. Heine,Lex M. Bouter,Nico Westerhof,Coen D.A. Stehouwer.Hypertension: Journal of the American Heart Association . 2004 (2)

[8]

Association Between Arterial Stiffness and Atherosclerosis: The Rotterdam Study[J] . Nicole M. van Popele,Diederick E. Grobbee,Michiel L. Bots,Roland Asmar,Jirar Topouchian,Robert S. Reneman,Arnold P.G. Hoeks,Deidre A.M. van der Kuip,Albert Hofman,Jacqueline C.M. Witteman.Stroke: Journal of the American Heart Association . 2001 (2)

[9]

Aortic Distensibility in Normotensive, Untreated and Treated Hypertensive Patients[J] . Roland Asmar,Athanase Benetos,G＆eacute,rard London,Christian Hugue,Yves Weiss,Jirar Topouchian,Brigitte Laloux,Michel Safar.Blood Pressure . 1995 (1)

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