cDNA表达点阵研究苦参碱诱导K562细胞凋亡基因表达的改变

被引：10

作者：

张永清

黄高升

冯骥良

王哲

杨国荣

机构：

[1] 第四军医大学基础部病理学教研室

[2] 第四军医大学基础部病理学教研室陕西西安

[3] 陕西西安

来源：

第四军医大学学报 | 2002年 / 09期

关键词：

苦参碱; K562细胞; 凋亡; 基因变化;

D O I：

暂无

中图分类号：

R733.7 [白血病];

学科分类号：

100214 ;

摘要：

K562 cells can be induced to apoptosis by matrine, but the mechanism remains unknown. cDNA expression array was applied to study genes' expression change of K562 cells induced by matrine. Expression of 16 genes was decreased, 11 of them belonged to genes of cyclins or CDKs, 4 of them were anti apoptosis genes, and expression of 19 genes was increased, 11 of them were proapoptotic genes.

引用

页码：764 / 764

页数：1