氟哌啶醇与利培酮对精神分裂症患者生活质量的影响

Objective: To compare the effects between haloperidol and rieperidone on quality of life in patients with schizophrenia. Methods: The patients with schizophrenia treated respectively by haloperidol and risperidone were compared by double blind method. The General Quality of Life Inventory (GQOLI) was used to evaluate the life quality, while the Positive and Negative Symptoms Scale (PANSS) and the Treatment Emergent Symptom Scale (TESS) were used to assess the efficacy and side effects. Results: The risperidone group showed better effects than the haloperidol group in the domains of physical function ,mental health and social function The difference was significant (P<0.01). Conclusion: The quality of life of Schizophrenic patients treated by haloperidol were poorer than that of risperidone.