严重烧伤患者TNF、IL-6和IL-8水平的变化及相关性研究

被引:13
作者
Zhu Keqing
Zhang Suojiang
机构
[1] 福建医科大学附属协和医院省烧伤研究所
[2] 福州
关键词
烧伤; 肿瘤坏死因子; 白细胞介素-6; 白细胞介素-8;
D O I
暂无
中图分类号
R644 [烧伤及烫伤(灼伤)];
学科分类号
摘要
目的:研究烧伤后细胞因子的变化规律及其相关性,并探讨其临床意义.方法:采用放射免疫法和ELISA法检测烧伤患者血中TNF、IL-6及IL-8水平.结果:烧伤后血中TNF、IL-6及IL-8水平均显著高于正常对照组(P<0.001),且持续时间较长(4~5周),它们间呈正相关(P<0.01);同时,IL-6与烧伤总面积呈正相关.结论:细胞因子活性的检测有助于病情的评估及预后判断,尤其是大面积烧伤患者.
引用
收藏
页码:387 / 388
页数:2
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