共 22 条
[1]
Huntingtheemesisand efficacytargetsofPDE4inhibitors:identificationofthe photoaffinityprobe8 (3azidophenyl)6[(4iodo1H1imidazolyl)methyl]quinoline (APIIMQ). MacdonaldD,PerrierH,LiuS,etal. Journal of Medicinal Chemistry . 2000
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Phosphodiesterase4inhibitors antiinflammatorytherapyforchronicobstructivepulmonary diseaseatlast?. KerstjensAM,TimensW. AmJRespirCritCareMed . 2003
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Airwaysinflammation andCOPD:epithelial neutrophilinteractions. CarolA,PettersenMS,KennethB,etal. Chest . 2002
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Oxidants/antioxidantsandCOPD. MacNeeW. Chest . 2000
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Cellularandstructural basesofchronicobstructivepulmonarydisease. SaettaM,TuratoG,MaestrelliP,etal. AmJRespirCrit Med . 2001
[6]
Theselective phosphodiesterase4inhibitorRP73401reducedmatrix metalloproteinase9activityandtransforminggrowthfactorβreleaseduringacutelunginjuryinmice:theroleofthebalance betweentumornecrosisfactorαandinterleukin10. CorbelM,No¨ellaG,J啨r^omeL,etal. TheJournal ofPharmacologyandExperimentalTherapeutics . 2002
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Inflammationoftheairwaysand lungParenchymainCOPD:roleofTcells. CosioMG,MajoJ,CosioMG. Chest . 2002
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Enhanceexpressionof vascularendothelialgrowthfactorinpulmonaryareriesof smokersandpatientswithmoderatechronicobstructive pulmonarydisease. SantosS,PeinadoVI,Ram姫rezJ,etal. AmJRespirCritCareMed . 2003
[9]
PDE4inhibitorsattenuate fibroblastchemotaxisandcontractionofnativecollagengels. KohyamaT,LiuX,WenFQ,etal. Am JRespirCellMolBiol . 2002
[10]
Phosphodiesterase4inhibitor cilomilastinhibitsfibroblast mediatedcollagengeldegradation inducedbytumornecrosisfactorαandneutrophilelastase. KohyamaT,LiuX,ZhuYK,etal. AmJ RespirCellMolBiol . 2002