B7-H3的作用机制及其在非小细胞肺癌中的研究新进展

被引：4

作者：

王萱

南丁阿比雅思

杨悦

李晓梅

机构：

[1] 哈尔滨医科大学附属肿瘤医院病理科

来源：

现代肿瘤医学 | 2019年 / 27卷 / 24期

关键词：

B7-H3; 非小细胞肺癌; 机制研究; 肿瘤易感性;

D O I：

暂无

中图分类号：

R734.2 [肺肿瘤];

学科分类号：

100117 [系统生物医学];

摘要：

肺癌是目前世界上癌症相关性死亡的主要原因之一。其中最常见的类型为非小细胞肺癌(non-small cell lung cancer,NSCLC)。肺癌患者预后不佳,因此探索新型治疗方案对提高患者预后来说是非常必要的。据研究,共刺激分子B7-H3(CD276)在抗肿瘤免疫中起着重要的作用,而免疫系统的调节机制在抑制肿瘤微环境中的抗肿瘤T细胞介导的免疫反应中起着重要作用。本文阐述了B7-H3的作用机制及其在非小细胞肺癌微环境中表达的临床意义。

引用

收藏

页码：4485 / 4488

页数：4

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