细胞焦亡与癌症关系的研究进展

被引：9

作者：

乔菲

郝蕾

晁旭

机构：

[1] 陕西中医药大学

来源：

中华实用诊断与治疗杂志 | 2018年 / 32卷 / 11期

关键词：

癌症; 细胞焦亡; 半胱天冬氨酸蛋白酶;

D O I：

暂无

中图分类号：

R730.2 [肿瘤病理学、病因学];

学科分类号：

100214 [肿瘤学];

摘要：

细胞焦亡是一种由炎性体引起细胞裂解的程序性细胞死亡方式,其特征是质膜破裂后释放细胞内容物和促炎介质,进一步导致细胞死亡。焦亡反应依赖于半胱天冬氨酸蛋白酶caspase-1、-4、-5、-11的活性,并伴随着炎性反应的发生。细胞焦亡与癌症关系密切,对焦亡机制及与癌症的关系进行深入研究,有助于了解癌症的发生、发展机制,为癌症防治提供新的方法。本文就细胞焦亡与癌症关系的研究进展作一综述。

引用

页码：1132 / 1134

页数：3

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