肝癌介入治疗用微粒型栓塞剂的研究进展

被引:21
作者
刘影
张跃伟
机构
[1] 大连大学附属中山医院介入治疗科
关键词
微粒型栓塞剂; 肝癌; 肝动脉化疗栓塞术;
D O I
暂无
中图分类号
R735.7 [肝肿瘤];
学科分类号
100112 [医学生物化学与分子生物学];
摘要
近年来,多项临床随机对照研究表明与保守治疗相比经导管肝动脉化疗栓塞术(TACE)治疗中晚期肝癌(HCC)取得了良好的临床疗效。随着栓塞材料的发展,新型微粒栓塞剂因具有生物相容性、药物缓释作用等优点而成为临床研究的热点,有望进一步提升TACE治疗肝癌的临床疗效。目前国内外已有多种微粒型栓塞剂应用于临床,现将其生物特性及临床疗效做如下综述。
引用
收藏
页码:969 / 972
页数:4
相关论文
共 13 条
[1]
不可手术切除的肝细胞癌的疗效评价标准——改良RECIST标准更可靠 [J].
姚雪松 ;
李槐 .
介入放射学杂志, 2012, 21 (03) :177-179
[2]
白芨作为血管栓塞剂的应用 [J].
李裕波 ;
林进令 ;
刘志明 .
介入放射学杂志, 2010, 19 (10) :835-838
[3]
Hepatocellular carcinoma [J].
Forner, Alejandro ;
Llovet, Josep M. ;
Bruix, Jordi .
LANCET, 2012, 379 (9822) :1245-1255
[4]
Survival of patients with hepatocellular carcinoma treated by transarterial chemoembolisation (TACE) using Drug Eluting Beads. Implications for clinical practice and trial design [J].
Burrel, Marta ;
Reig, Maria ;
Forner, Alejandro ;
Barrufet, Marta ;
Rodriguez de Lope, Carlos ;
Tremosini, Silvia ;
Ayuso, Carmen ;
Llovet, Josep M. ;
Isabel Real, Maria ;
Bruix, Jordi .
JOURNAL OF HEPATOLOGY, 2012, 56 (06) :1330-1335
[5]
Changes in Liver and Spleen Volumes and Liver Function after Radioembolization with Yttrium-90 Resin Microspheres [J].
Nosher, John L. ;
Ohman-Strickland, Pamela A. ;
Jabbour, Salma ;
Narra, Venkat ;
Nosher, Brittany .
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2011, 22 (12) :1706-1713
[6]
Comparative Analysis of the Safety and Efficacy of Transcatheter Arterial Chemoembolization and Yttrium-90 Radioembolization in Patients with Unresectable Hepatocellular Carcinoma [J].
Lance, Craig ;
McLennan, Gordon ;
Obuchowski, Nancy ;
Cheah, Grace ;
Levitin, Abraham ;
Sands, Mark ;
Spain, James ;
Srinivas, Shyam ;
Shrikanthan, Sankaran ;
Aucejo, Federico N. ;
Kim, Richard ;
Menon, K. V. Narayanan .
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2011, 22 (12) :1697-1705
[7]
Radioembolization Results in Longer Time-to-Progression and Reduced Toxicity Compared With Chemoembolization in Patients With Hepatocellular Carcinoma [J].
Salem, Riad ;
Lewandowski, Robert J. ;
Kulik, Laura ;
Wang, Edward ;
Riaz, Ahsun ;
Ryu, Robert K. ;
Sato, Kent T. ;
Gupta, Ramona ;
Nikolaidis, Paul ;
Miller, Frank H. ;
Yaghmai, Vahid ;
Ibrahim, Saad M. ;
Senthilnathan, Seanthan ;
Baker, Talia ;
Gates, Vanessa L. ;
Atassi, Bassel ;
Newman, Steven ;
Memon, Khairuddin ;
Chen, Richard ;
Vogelzang, Robert L. ;
Nemcek, Albert A. ;
Resnick, Scott A. ;
Chrisman, Howard B. ;
Carr, James ;
Omary, Reed A. ;
Abecassis, Michael ;
Benson, Al B., III ;
Mulcahy, Mary F. .
GASTROENTEROLOGY, 2011, 140 (02) :497-U205
[8]
Bland Embolization in Patients with Unresectable Hepatocellular Carcinoma Using Precise, Tightly Size-Calibrated, Anti-Inflammatory Microparticles: First Clinical Experience and One-Year Follow-Up [J].
Bonomo, Guido ;
Pedicini, Vittorio ;
Monfardini, Lorenzo ;
Della Vigna, Paolo ;
Poretti, Dario ;
Orgera, Gianluigi ;
Orsi, Franco .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 2010, 33 (03) :552-559
[9]
Experimental Liver Embolization with Four Different Spherical Embolic Materials: Impact on Inflammatory Tissue and Foreign Body Reaction [J].
Stampfl, Ulrike ;
Stampfl, Sibylle ;
Bellemann, Nadine ;
Sommer, Christof-Matthias ;
Lopez-Benitez, Ruben ;
Thierjung, Heidi ;
Radeleff, Boris ;
Berger, Irina ;
Richter, Goetz M. .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 2009, 32 (02) :303-312
[10]
Transarterial Chemoembolization for Hepatocellular Carcinoma with Drug-Eluting Microspheres: Preliminary Results from an Italian Multicentre Study [J].
Grosso, Maurizio ;
Vignali, Claudio ;
Quaretti, Pietro ;
Nicolini, Antonio ;
Melchiorre, Fabio ;
Gallarato, Gabriele ;
Bargellini, Irene ;
Petruzzi, Pasquale ;
Massa Saluzzo, Cesare ;
Crespi, Silvia ;
Sarti, Ilaria .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 2008, 31 (06) :1141-1149