Th17细胞的分化调控与自身免疫性疾病

被引:13
作者
郭静雅
邱玉华
机构
[1] 苏州大学医学部免疫学系
关键词
Th17细胞; IL-17; 自身免疫性疾病;
D O I
暂无
中图分类号
R593.2 [自身免疫性疾病、结缔组织疾病];
学科分类号
摘要
Th17细胞是最近发现的一种在分化和功能上均不同于Th1和Th2的新型CD4+T细胞亚群。该群细胞以主要分泌细胞因子IL-17而得名。IL-6、TGF-β、IL-21及IL-23等对Th17细胞的分化调控发挥重要作用。研究表明,Th17细胞可参与多种自身免疫性疾病的发生、发展与转归。
引用
收藏
页码:249 / 252
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