宫颈腺癌105例临床病例分析

被引:14
作者
魏梅
梁立治
袁颂华
颜笑健
杜佩妍
沈扬
机构
[1] 中山大学肿瘤防治中心妇科
关键词
腺癌; 宫颈; 预后; 治疗; 卵巢转移;
D O I
暂无
中图分类号
R737.33 [子宫肿瘤];
学科分类号
摘要
目的:宫颈腺癌是除鳞癌外最常见的一种病理类型,预后欠佳,近几十年发病率呈上升趋势并趋向年轻化。本研究旨在探讨宫颈腺癌预后的相关因素、卵巢转移情况及治疗方法。方法:回顾性分析中山大学肿瘤防治中心妇科1970年1月~2002年12月收治的105例宫颈腺癌临床病理资料。结果:前16年内患者中位年龄50岁,后16年内患者中位年龄46岁。按FIGO分期Ⅰ期、Ⅱ期、Ⅲ期患者五年生存率分别为58.24%、49.48%、21.20%。单因素、多因素分析均显示肿瘤大小、有无淋巴结转移与预后相关。临床分期Ⅱ期的患者,单纯手术组、手术加放疗组预后较单纯放疗、手术加化疗、手术加放疗加化疗预后佳(P=0.0014)。68例行双侧卵巢切除,3例卵巢转移,转移率4.41%。结论:宫颈腺癌发病呈年轻化趋势,预后较鳞癌差。肿瘤大小、有无淋巴结转移是预后相关因素。手术治疗效果优于放射治疗。中晚期患者卵巢转移率高,但对早期宫颈腺癌的年轻患者,仍可考虑保留一侧正常卵巢。
引用
收藏
页码:1227 / 1230
页数:4
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