铁在帕金森病发病机制中的作用及其MRI测量

被引：17

作者：

张静 ^{[1
,2
]}

张云亭 ^{[1
]}

机构：

[1] 天津医科大学总医院放射科

[2] 兰州大学第二医院放射科

来源：

国际医学放射学杂志 | 2009年 / 32卷 / 04期

关键词：

铁; 帕金森病; 磁共振成像;

D O I：

暂无

中图分类号：

R742.5 [震颤麻痹综合征]; R445.2 [核磁共振成像];

学科分类号：

100204 [神经病学]; 100231 [临床病理学];

摘要：

大量研究均证实帕金森病病人黑质铁异常沉积,随着对铁氧化应激损伤认识的深入,铁在帕金森病发病机制中的作用日益受到研究者的重视。MRI是唯一可以在活体定量检测脑铁含量的技术,在帕金森病的诊断、治疗及疗效随访中具有潜在的重要价值。就铁在脑内的代谢、在帕金森病中的病理机制及MRI定量测量的研究进展予以综述。

引用

页码：343 / 346

页数：4

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