血清胃蛋白酶原、胃泌素-17、幽门螺杆菌抗体检测对萎缩性胃炎和胃癌的诊断价值

被引：76

作者：

赵建业

朱春平

李兆申

机构：

[1] 第二军医大学附属长海医院消化科

来源：

胃肠病学 | 2016年 / 21卷 / 06期

关键词：

胃蛋白酶原类; 胃泌素类; 胃炎,萎缩性; 胃肿瘤; 幽门螺杆菌; 诊断;

D O I：

暂无

中图分类号：

R735.2 [胃肿瘤]; R573.32 [];

学科分类号：

100112 [医学生物化学与分子生物学];

摘要：

诸多研究表明,血清胃蛋白酶原(PG)和胃泌素-17(G-17)水平变化能反映胃黏膜组织学状态,可作为胃底腺黏膜的血清学活检,并可将血清PGⅠ水平和PGⅠ/PGⅡ比值(PGR)下降以及G-17水平升高作为胃癌高风险指标应用于临床评估。幽门螺杆菌(Hp)感染可导致慢性活动性胃炎,随着炎症进展,可引起黏膜萎缩、肠化生。本文就血清PG、G-17、Hp抗体检测对萎缩性胃炎和胃癌的诊断价值作一综述。

引用

页码：376 / 379

页数：4

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