病理性瘢痕的治疗研究进展及展望

被引:18
作者
武文博 [1 ]
郭丽丽 [2 ]
欧阳军 [1 ,3 ]
机构
[1] 新疆维吾尔自治区石河子大学医学院第一附属医院急诊外科
[2] 郑州大学第一附属医院整形外科
[3] 新疆维吾尔自治区石河子大学医学院第一附属医院烧伤整形科
关键词
病理性瘢痕; 增生性瘢痕; 瘢痕疙瘩; 硅胶; 类固醇; 治疗;
D O I
10.13919/j.issn.2095-6274.2019.05.014
中图分类号
R622 [整形手术学];
学科分类号
100224 [整形外科学];
摘要
瘢痕是人体创伤修复过程中的必然产物,从广义上来讲,没有瘢痕就没有创伤的愈合。针对病理性瘢痕的研究是整形外科的重难点研究项目之一。目前研究认为病理性瘢痕的形成过程是成纤维细胞、肌成纤维细胞、多种细胞因子、细胞生长因子、胶原的代谢与排列失常、毛细血管生成、氧自由基、热休克蛋白及组织空间结构等多种因素共同参与创面修复与瘢痕组织的形成,属于多因一果的发病机制。笔者回顾了国内外最新文献对于病理性瘢痕分类和治疗方法的研究,至今尚未有分类和治疗方法的"金标准"。本文依据国际上病理性瘢痕最新的分类方法,针对每一种分型的病理性瘢痕在治疗研究进展及治疗理念上作一综述。
引用
收藏
页码:295 / 300
页数:6
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