老年高血压分型与健康老人血浆同型半胱氨酸、神经肽Y及血脂水平的比较研究

被引:24
作者
李浩
宋春生
刘方州
徐力然
崔玲
罗增刚
刘芳
机构
[1] 中国中医研究院西苑医院
[2] 河南中医药研究院附属医院
[3] 中国中医研究院西苑医院 北京
[4] 北京
关键词
老年高血压; 同型半胱氨酸; 神经肽Y; 血脂;
D O I
暂无
中图分类号
R544.1 [高血压];
学科分类号
1002 ; 100201 ;
摘要
目的 探讨老年不同类型高血压患者与老年健康者之间的血浆同型半胱氨酸 (Hcy)、神经肽 Y(NPY)及血脂水平的差异。方法 对老年单纯收缩期高血压 (ISH) 36例、全期型高血压 (SDH) 31例、单纯舒张期高血压 (IDH) 34例及老年健康者 2 0例分别测取血浆 Hcy、NPY及血脂水平值 ,进行统计学处理分析其间的差异。结果 老年高血压患者血浆 Hcy及 NPY水平均高于老年健康组 (P<0 .0 1 ) ,且老年 ISH患者比老年 SDH和老年 IDH患者皆显著增高 (P<0 .0 1 )。但老年 SDH及 IDH两者血浆 NPY含量比较无差异 (P>0 .0 5) ,血脂代谢异常贯穿老年高血压发病的始终 ,但老年 ISH患者组 HDL- C较老年 SDH及 IDH患者明显降低 (P<0 .0 5,P<0 .0 1 ) ,而 ISH组 LDL- C较老年 IDH患者显著降低 (P<0 .0 5)。结论 控制患者血浆中 Hcy及 NPY浓度对预防老年高血压 ,尤其是 ISH的发生或发展可能有积极作用 ,调节脂代谢异常适用于各类型老年高血压的防治。
引用
收藏
页码:496 / 498
页数:3
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