胰岛素样生长因子-1与糖尿病

被引:3
作者
付秀美
付文亮
陈志宏
宋成军
薛景凤
机构
[1] 承德医学院
关键词
IGF-1; 糖尿病; 进展;
D O I
10.15921/j.cnki.cyxb.2008.03.035
中图分类号
R587.1 [糖尿病];
学科分类号
100201 [内科学];
摘要
<正>1957年,Salmon和Daughaday在研究生长激素(GH)的作用时发现,GH对机体的促生长作用是由另一类物质所介导的,这类物质具有下列生物活性:不受抑制的胰岛素样作用,GH可调节的硫酸化作用,多重的促细胞增殖作用。由于它介导GH的生物作用,曾被称为生长介素
引用
收藏
页码:312 / 314
页数:3
相关论文
共 8 条
[1]
GH-IGF-1轴的作用机制 [J].
赵咏梅 ;
毛萌 .
四川医学, 2005, (07) :808-810
[2]
Insulin-like growth factorⅠpreventsmannitolinduced degradation of focal adhesion kinase andAkt..Kim B;FeldmanEL;.BiolChem.2002, 30
[3]
Association of serum levels of IGF-I and IGFBP-1 with renal function in patients with type 2 diabetes mellitus [J].
Akturk, Mujde ;
Arslan, Metin ;
Altinova, Alev ;
Ozdemir, Aysegul ;
Ersoy, Reyhan ;
Yetkin, Ilhan ;
Ayvali, Elif ;
Gonen, Sevim ;
Toruner, Fusun .
GROWTH HORMONE & IGF RESEARCH, 2007, 17 (03) :186-193
[4]
Effects of insulin-like growth factor binding proteins in bone&mdash;a matter of cell and site.[J].A. Hoeflich;W. G&ouml;tz;A. M. Lichanska;M. Bielohuby;B. T&ouml;nshoff;D. Kiepe.Archives of Physiology and Biochemistry.2007, 3
[5]
Insulin-like growth factor I induced survival of axotomized olfactory neurons in the chick.[J].M Mathonnet;I Comte;F Lalloué;C Ayer-Le Lièvre.Neuroscience Letters.2001, 2
[6]
Anti-angiogenic therapy of proliferative diabetic retinopathy.[J].Danis;Ciulla;Criswell;Pratt.Expert Opinion on Pharmacotherapy.2001, 3
[7]
Systemic Levels Contribute Significantly to Increased Intraocular IGF-I; IGF-II and IFG-BP3 in Proliferative Diabetic Retinopathy.[J].J. Spranger;J. Bühnen;V. Jansen;M. Krieg;R. Meyer-Schwickerath;W. Blum;H. Schatz;A. Pfeiffer.Horm Metab Res.2000, 5
[8]
Diabetes-induced suppression of IGF-1 and its receptor mRNA levels in rat superior cervical ganglia [J].
Bitar, MS ;
Pilcher, CWT ;
Khan, I ;
Waldbillig, RJ .
DIABETES RESEARCH AND CLINICAL PRACTICE, 1997, 38 (02) :73-80