影响脑梗死静脉溶栓预后的相关因素分析

被引:7
作者
张春阳
机构
[1] 天津市第五中心医院
关键词
急性脑梗死; 静脉溶栓; rt-PA; 糖尿病;
D O I
暂无
中图分类号
R743.33 [脑栓塞];
学科分类号
1002 ;
摘要
目的探讨可能影响脑梗死患者静脉溶栓预后的因素。方法 69例急性脑梗死患者给予阿替普酶(recombi-nant tissue plasminogen activator,rt-PA)治疗,以90d时改良Rankin量表(mRS)评分作为疗效指标,0~1分者为预后良好,2~6分包括死亡为预后不佳,并对影响因素做Logistic回归分析。结果预后良好23例(33.3%),预后不良46例(66.67%)。经回归分析显示糖尿病、颈内或大脑中动脉闭塞为预后的独立预测因素。结论脑梗死合并糖尿病、颈内或大脑中动脉闭塞患者静脉溶栓预后不佳。
引用
收藏
页码:13 / 16
页数:4
相关论文
共 10 条
[1]   Carotid Duplex Ultrasonography Can Predict Outcome of Intravenous Alteplase Therapy for Hyperacute Stroke [J].
Koga, Masatoshi ;
Toyoda, Kazunori ;
Nakashima, Takahiro ;
Hyun, Boo-Han ;
Uehara, Toshiyuki ;
Yokota, Chiaki ;
Nagatsuka, Kazuyuki ;
Naritomi, Hiroaki ;
Minematsu, Kazuo .
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 2011, 20 (01) :24-29
[2]  
Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials[J] . Kennedy R Lees,Erich Bluhmki,Rüdiger von Kummer,Thomas G Brott,Danilo Toni,James C Grotta,Gregory W Albers,Markku Kaste,John R Marler,Scott A Hamilton,Barbara C Tilley,Stephen M Davis,Geoffrey A Donnan,Werner Hacke.The Lancet . 2010 (9727)
[3]  
Expansion of the Time Window for Treatment of Acute Ischemic Stroke With Intravenous Tissue Plasminogen Activator: A Science Advisory From the American Heart Association/American Stroke Association[J] . Gregory J. del Zoppo,Jeffrey L. Saver,Edward C. Jauch,Harold P. Adams.Stroke . 2009 (8)
[4]   Admission Hyperglycemia Predicts a Worse Outcome in Stroke Patients Treated With Intravenous Thrombolysis [J].
Poppe, Alexandre Y. ;
Majumdar, Sumit R. ;
Jeerakathil, Thomas ;
Ghali, William ;
Buchan, Alastair M. ;
Hill, Michael D. .
DIABETES CARE, 2009, 32 (04) :617-622
[5]   Dynamic of hyperglycemia as a predictor of stroke outcome in the ECASS-II trial [J].
Yong, Mei ;
Kaste, Markku .
STROKE, 2008, 39 (10) :2749-2755
[6]  
Clinical and Tissue Response to Intravenous Thrombolysis in Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion: An MRI Study[J] . Stroke . 2008 (5)
[7]   Site of arterial occlusion identified by transcranial Doppler predicts the response to intravenous thrombolysis for stroke [J].
Saqqur, Maher ;
Uchino, Ken ;
Demchuk, Andrew M. ;
Molina, Carlos A. ;
Garami, Zsolt ;
Calleja, Sergio ;
Akhtar, Naveed ;
Orouk, Finton O. ;
Salam, Abdul ;
Shuaib, Ashfaq ;
Alexandrov, Andrei V. .
STROKE, 2007, 38 (03) :948-954
[8]  
Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion: An Independent Predictor of Poor Outcome After Systemic Thrombolysis[J] . Marta Rubiera,Marc Ribo,Raquel Delgado-Mederos,Esteban Santamarina,Pilar Delgado,Joan Montaner,José Alvarez-Sabín,Carlos A. Molina.Stroke . 2006 (9)
[9]   Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke [J].
Marder, Victor J. ;
Chute, Dennis J. ;
Starkman, Sidney ;
Abolian, Anna M. ;
Kidwell, Chelsea ;
Liebeskind, David ;
Ovbiagele, Bruce ;
Vinuela, Fernando ;
Duckwiler, Gary ;
Jahan, Reza ;
Vespa, Paul M. ;
Selco, Scott ;
Rajajee, Venkatakrishna ;
Kim, Dojin ;
Sanossian, Nerses ;
Saver, Jeffrey L. .
STROKE, 2006, 37 (08) :2086-2093
[10]  
Guidelines for management of ischaemic stroke and transient ischaemic attack 2008 .2 European Stroke Organisation(ESO) Executive Committee,ESO Writing Committee. Cerbrovasc Dis . 2008