关节镜清理术配合盐酸氨基葡萄糖治疗轻度单侧膝骨关节炎的疗效研究

被引:9
作者
陈小兵
崔静
机构
[1] 阿勒泰地区人民医院外二科
关键词
关节镜清理术; 盐酸氨基葡萄糖; 骨关节炎,膝;
D O I
暂无
中图分类号
R687.4 [关节手术];
学科分类号
100220 [骨科学];
摘要
目的探讨关节镜清理术配合盐酸氨基葡萄糖对膝骨关节炎的治疗作用。方法 2009年6月-2011年6月纳入轻度膝骨关节炎(AhlbackⅠ级)患者135例,随机分成3组。A组(n=45)接受关节镜清理术治疗;B组(n=45)口服盐酸氨基葡萄糖胶囊治疗;C组((n=45)先行关节镜清理术治疗,术后口服盐酸氨基葡萄糖胶囊。观察3组Lequesne评分和WOMAC指数,用以评价治疗效果。结果成功随访患者123例,随访时间8个月。治疗后各组Lequesne评分和WOMAC指数较治疗前均显著好转(P<0.01),其中治疗后C组好转较A组和B组具有显著性(P<0.01),但B组和C组之间差异无统计学意义(P>0.05)。结论关节镜清理术配合盐酸氨基葡萄糖,较之单用关节镜清理术或盐酸氨基葡萄糖,对膝骨关节炎的治疗有更好的效果。
引用
收藏
页码:1541 / 1544
页数:4
相关论文
共 8 条
[1]
盐酸氨基葡萄糖治疗膝骨关节炎的随机对照研究 [J].
苏江 ;
张晶 ;
吴侗 ;
周彬 .
华西医学, 2012, 27 (12) :1776-1779
[2]
Factors affecting the outcome of arthroscopy in medial-compartment osteoarthritis of the knee [J].
Spahn, Gunter ;
Mueckley, Thomas ;
Kahl, Enrico ;
Hofmann, Gunther O. .
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY, 2006, 22 (11) :1233-1240
[3]
Effectiveness of glucosamine for symptoms of knee osteoarthritis: Results from an Internet-based randomized double-blind controlled trial [J].
McAlindon, T ;
Formica, M ;
LaValley, M ;
Lehmer, M ;
Kabbara, K .
AMERICAN JOURNAL OF MEDICINE, 2004, 117 (09) :643-649
[4]
Influence of obesity on outcome after knee arthroscopy [J].
Harrison, MM ;
Morrell, J ;
Hopman, WM .
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY, 2004, 20 (07) :691-695
[5]
Arthroscopic washout of the knee—a 5-year survival analysis.[J].J Bernard;M Lemon;M.H Patterson.The Knee.2003, 3
[6]
The results of arthroscopic lavage and debridement of osteoarthritic knees based on the severity of degeneration.[J].Robert W. Jackson;Chad Dieterichs.Arthroscopy: The Journal of Arthroscopic and Related Surgery.2003, 1
[7]
Arthroscopic debridement for the treatment of osteoarthritis of the knee: 2-and 5-year results [J].
Fond, J ;
Rodin, D ;
Ahmad, S ;
Nirschl, RP .
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY, 2002, 18 (08) :829-834
[8]
Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial [J].
Reginster, JY ;
Deroisy, R ;
Rovati, LC ;
Lee, RL ;
Lejeune, E ;
Bruyere, O ;
Giacovelli, G ;
Henrotin, Y ;
Dacre, JE ;
Gossett, C .
LANCET, 2001, 357 (9252) :251-256