修订版美国国立卫生研究院卒中量表评估幕上占位患者镇静相关局部神经功能缺陷的诊断价值

被引:30
作者
马婷婷
张星月
彭宇明
林楠
机构
[1] 首都医科大学附属北京天坛医院麻醉科
关键词
幕上占位; 神经功能缺陷; 镇静; 美国国立卫生院卒中量表;
D O I
暂无
中图分类号
R614 [麻醉学];
学科分类号
100217 [麻醉学];
摘要
目的观察修订版美国国立卫生研究院卒中量表(modified National Institutes of Health Stroke Scale, mNIHSS)在评估幕上占位患者的镇静相关局部神经功能缺陷时, 对其诊断性指标的影响。方法研究纳入既往通过美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale, NIHSS)行轻度镇静后神经功能评估的幕上占位患者, 对镇静诱发的NIHSS变化阳性(NIHSS改变≥2分)及阴性(NIHSS改变<2分)患者使用mNIHSS进行重新评估, 以NIHSS改变的结果为标准, 评价mNIHSS对检测幕上占位患者镇静诱发局部神经功能缺陷的诊断价值。结果使用NIHSS评估发现:与镇静前比较, 丙泊酚和咪达唑仑镇静后肢体运动和肢体共济两项神经功能评分明显升高, 芬太尼和右美托咪定镇静后肢体运动评分明显升高, 差异有统计学意义(P<0.05)。NIHSS评分为阴性的患者其mNIHSS均为阴性;54例NIHSS评分为阳性的患者中有51例患者mNIHSS评分为阳性, 3例患者mNIHSS评分为阴性。使用mNIHSS评估幕上占位患者镇静诱发神经功能缺陷的敏感度为94.44%, 特异性为100%, 漏诊率为5.56%, 误诊率为0, 约登指数为0.944, Kappa=0.95。结论 mNIHSS简便易行, 用于评估幕上占位患者的镇静相关神经功能改变的敏感度和特异性高, 且与NIHSS的评估一致性较高, 但存在一定的漏诊率。
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