骨不连治疗方法的研究进展

被引:11
作者
吴文明
唐佩福
机构
[1] 中国人民解放军总医院骨科
关键词
骨不连; 骨愈合机制; 间充质干细胞;
D O I
暂无
中图分类号
R683 [骨折、骨的损伤];
学科分类号
100220 [骨科学];
摘要
美国AAOS诊断骨不连定义:是指骨折后至少9个月且连续3个月动态观察未见到骨折有明显的愈合征象,延迟愈合或者骨不连概率为5%10%。目前临床上治疗骨不连仍以手术治疗、药物治疗、物理治疗、分子生物治疗以及中医中药治疗等为主,近年来随着对骨愈合基本过程、机制的研究及对干细胞研究的关注,认识到了骨髓间充质干细胞在骨折愈合机制中的机理,发现了一些干细胞对骨愈合的调控机制。对骨折愈合过程、机制及骨不连治疗方法选择做一综述概括,探讨骨髓间充质干细胞治疗骨不连的有效性及可能性,为该疾病的临床治疗决策提供相关理论依据。
引用
收藏
页码:126 / 129
页数:4
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