尿激酶、阿替普酶与瑞替普酶溶栓治疗肺栓塞对比研究

被引:14
作者
陈强
李楠
黄晨
朱家庭
吴友华
马林
徐宝华
机构
[1] 大连市第三人民医院心内二科
关键词
肺栓塞; 尿激酶; 阿替普酶; 瑞替普酶; 溶栓治疗;
D O I
暂无
中图分类号
R563.5 [肺栓塞];
学科分类号
1002 ; 100201 ;
摘要
目的:评价急诊应用尿激酶、阿替普酶与瑞替普酶溶栓治疗肺栓塞的疗效。方法:回顾性分析我院2008年1月2013年1月急诊收治的急性大面积肺栓塞58例,分别给予静脉溶栓治疗,其中尿激酶18例,阿替普酶28例,瑞替普酶12例,观察三组溶栓有效率、出血不良反应、住院期间的病死率。结果:尿激酶组有效率77.6%,轻度出血4例,中度出血0例,住院期间死亡0例;阿替普酶组有效率82.3%,轻度出血6例,中度出血0例,住院期间死亡0例;瑞替普酶组有效率86.5%,轻度出血2例,中度出血0例,住院期间死亡0例。结论:尿激酶、阿替普酶与瑞替普酶溶栓治疗肺栓塞均有较高的有效性及安全性,阿替普酶及瑞替普酶较尿激酶的疗效及安全性好,出血风险较尿激酶低。
引用
收藏
页码:47+87 / 47 +87
页数:2
相关论文
共 4 条
[1]  
Clinical Characteristics, Management, and Outcomes of Patients Diagnosed With Acute Pulmonary Embolism in the Emergency Department[J] . Charles V. Pollack,Donald Schreiber,Samuel Z. Goldhaber,David Slattery,John Fanikos,Brian J. O’Neil,James R. Thompson,Brian Hiestand,Beau A. Briese,Robert C. Pendleton,Chadwick D. Miller,Jeffrey A. Kline.Journal of the American College of Cardiology . 2011 (6)
[2]  
Management of Massive and Submassive Pulmonary Embolism, Iliofemoral Deep Vein Thrombosis, and Chronic Thromboembolic Pulmonary Hypertension: A Scientific Statement From the American Heart Association[J] . Michael R. Jaff,M. Sean McMurtry,Stephen L. Archer,Mary Cushman,Neil Goldenberg,Samuel Z. Goldhaber,J. Stephen Jenkins,Jeffrey A. Kline,Andrew D. Michaels,Patricia Thistlethwaite,Suresh Vedantham,R. James White,Brenda K. Zierler.Circulation . 2011 (16)
[3]  
Clinical Predictors for Fatal Pulmonary Embolism in 15 520 Patients With Venous Thromboembolism: Findings From the Registro Informatizado de la Enfermedad TromboEmbolica venosa (RIETE) Registry[J] . Silvy Laporte,Patrick Mismetti,Hervé Décousus,Fernando Uresandi,Remedios Otero,Jose Luis Lobo,Manuel Monreal.Circulation . 2008 (13)
[4]   Modern management of acute myocardial infarction [J].
Brilakis, ES ;
Reeder, GS ;
Gersh, BJ .
CURRENT PROBLEMS IN CARDIOLOGY, 2003, 28 (01) :7-127