MR扩散峰度成像原理及其在中枢神经系统的初步应用

被引：17

作者：

程悦

沈文

机构：

[1] 天津市第一中心医院放射科

来源：

国际医学放射学杂志 | 2015年 / 01期

关键词：

扩散; 扩散张量成像; 扩散峰度成像; 非高斯分布; 中枢神经系统;

D O I：

暂无

中图分类号：

R445.2 [核磁共振成像]; R741 [神经病学];

学科分类号：

100207 ; 1002 ;

摘要：

通过对水分子扩散运动的测量,扩散张量成像(DTI)可以无创地对组织结构进行评价,而扩散峰度成像(DKI)是以DTI为基础,对生物组织内水分子扩散的非高斯分布特征进行定量分析,揭示组织结构细微改变。DKI较DTI能提供更多关于组织微观结构的信息。综述DKI的原理及其在中枢神经系统的应用,包括神经退行性疾病、创伤性脑损伤、缺血性脑卒中、胶质瘤、多发性硬化、脑发育等。

引用

页码：20 / 24

页数：5

共 22 条

[1]

Diffusional kurtosis imaging of cingulate fibers in Parkinson disease: Comparison with conventional diffusion tensor imaging[J] . Koji Kamagata,Hiroyuki Tomiyama,Yumiko Motoi,Masayoshi Kano,Osamu Abe,Kenji Ito,Keigo Shimoji,Michimasa Suzuki,Masaaki Hori,Atsushi Nakanishi,Ryohei Kuwatsuru,Keisuke Sasai,Shigeki Aoki,Nobutaka Hattori.Magnetic Resonance Imaging . 2013 (9)

[2] Diffusion Kurtosis Imaging to Detect Amyloidosis in an APP/PS1 Mouse Model for Alzheimer's Disease [J].

Vanhoutte, Greetje ;

Pereson, Sandra ;

Delgado y Palacios, Rafael ;

Guns, Pieter-Jan ;

Asselbergh, Bob ;

Veraart, Jelle ;

Sijbers, Jan ;

Verhoye, Marleen ;

Van Broeckhoven, Christine ;

Van der Linden, Annemie .

MAGNETIC RESONANCE IN MEDICINE, 2013, 69 (04) :1115-1121

[3]

Diffusional kurtosis imaging of normal-appearing white matter in multiple sclerosis: preliminary clinical experience[J] . Mariko Yoshida,Masaaki Hori,Kazumasa Yokoyama,Issa Fukunaga,Michimasa Suzuki,Koji Kamagata,Keigo Shimoji,Atsushi Nakanishi,Nobutaka Hattori,Yoshitaka Masutani,Shigeki Aoki.Japanese Journal of Radiology . 2013 (1)

[4]

Stratification of Heterogeneous Diffusion MRI Ischemic Lesion With Kurtosis Imaging: Evaluation of Mean Diffusion and Kurtosis MRI Mismatch in an Animal Model of Transient Focal Ischemia[J] . Jerry S. Cheung,Enfeng Wang,Eng H Lo,Phillip Zhe Sun.Stroke . 2012 (8)

[5]

Spatiotemporal dynamics of diffusional kurtosis, mean diffusivity and perfusion changes in experimental stroke[J] . Edward S. Hui,Fang Du,Shiliang Huang,Qiang Shen,Timothy Q. Duong.Brain Research . 2012

[6]

Shifting imaging targets in multiple sclerosis: From inflammation to neurodegeneration[J] . René M. Vigeveno,Oliver T. Wiebenga,Mike P. Wattjes,Jeroen J.G. Geurts,Frederik Barkhof.J. Magn. Reson. Imaging . 2012 (1)

[7]

Diffusion kurtosis as an in vivo imaging marker for reactive astrogliosis in traumatic brain injury[J] . Jiachen Zhuo,Su Xu,Julie L. Proctor,Roger J. Mullins,Jonathan Z. Simon,Gary Fiskum,Rao P. Gullapalli.Neuroimage . 2011 (1)

[8]

Preliminary evidence of altered gray and white matter microstructural development in the frontal lobe of adolescents with attention‐deficit hyperactivity disorder: A diffusional kurtosis imaging study[J] . Joseph A.Helpern,VitriaAdisetiyo,Maria F.Falangola,CaixiaHu,AdrianaDi Martino,KathleenWilliams,Francisco X.Castellanos,Jens H.Jensen.J. Magn. Reson. Imaging . 2010 (1)

[9] MR diffusion kurtosis imaging for neural tissue characterization [J].

Wu, Ed X. ;

Cheung, Matthew M. .

NMR IN BIOMEDICINE, 2010, 23 (07) :836-848

[10] MRI quantification of non-Gaussian water diffusion by kurtosis analysis [J].

Jensen, Jens H. ;

Helpern, Joseph A. .

NMR IN BIOMEDICINE, 2010, 23 (07) :698-710

← 1 2 3 →