脂质沉积性肌病二例报告

被引：6

作者：

曹佩芝

吕丹云

夏谦

吴淑平

机构：

[1] 北京友谊医院神经内科

[2] 国家体育委员会科学研究所运动医学研究室

[3] 北京市房山县第二人民医院神经内科

来源：

关键词：

肌疾病; 肉碱酰基转移酶类;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

1002 ;

摘要：

我们报道2例脂质沉积性肌病。肌肉活检光镜下油红 O 染色显示中性脂滴过量,电镜显示脂滴于肌原纤维间或肌膜下成行排列。经泼尼松治疗,2例病人症状明显改善。复习文献描述了Ⅰ、Ⅱ型脂质沉积性肌病临床、病理及肌电图特点。

引用

共 11 条

[1]

Carnitine deficiency of human skeletal muscle with associated lipid storage myopathy: a new syndrome. Engel A G,Angelini C. Science . 1973

[2]

Neurology[C]. The 5th International Congress of Pathophysiology,2006

[3]

Genetic muscle diseases. Ionasescu,Victor M D,et al. Genetics in neurology . 1983

[4]

Serum carnitine. An index of muscle destruction in man. DiMauro,S,Scott,C,Penn,AS,Rowland,LP. Archives of Neurology . 1973

[5]

Neurology[C]. The 5th International Congress of Pathophysiology,2006

[6]

Diseases of muscle. Kakulao B A,et al. . 1985

[7]

Lipid storage myopathy responsive to prednisone. Engel AG,Siekert RG. Archives of Neurology . 1972

[8]

Metabolic myopathies. DiMauro,S,Vinken,PJ,Bruyn,GW. Handbook of Clinical Neurology, vol 41, Diseases of Muscle, Part II . 1979

[9]

Myopathy associated with abnormal lipid metabolism in skeletal muscle. Bradley WGP,Hudgson D,Gardner-Medwin,et al. Lancet,The . 1969

[10]

Neurology[C]. The 5th International Congress of Pathophysiology,2006