邻苯二甲酸酯类化合物的体内代谢及毒性研究进展

被引：72

作者：

赵雅辉

王小逸

林兴桃

客慧明

赵靖强

任海荣

机构：

[1] 北京工业大学环境与能源工程学院

来源：

环境与健康杂志 | 2010年 / 27卷 / 02期

关键词：

邻苯二甲酸酯类; 邻苯二甲酸单酯; 代谢机制; 毒性;

D O I：

10.16241/j.cnki.1001-5914.2010.02.030

中图分类号：

R114 [卫生毒理];

学科分类号：

100235 [预防医学];

摘要：

由于邻苯二甲酸酯类在环境中普遍存在,其一级代谢物邻苯二甲酸单酯在一些环境中也被发现。研究表明邻苯二甲酸单酯在体内的生物活性并不降低,已造成了对人体的伤害,成为研究邻苯二甲酸酯类毒性的新热点。该文介绍了邻苯二甲酸酯的代谢机制,对邻苯二甲酸单酯的三致毒性、生殖发育毒性、对激素及核受体家族的影响进行了综述。

引用

页码：184 / 187

页数：4

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