雌激素受体及其介导的基因表达与调控

被引：30

作者：

卞倩

机构：

[1] 南京医科大学应用毒理研究所

来源：

国外医学妇产科学分册. | 2002年 / 06期

关键词：

雌激素; 雌激素受体; 基因表达调控;

D O I：

暂无

中图分类号：

R346 [];

学科分类号：

摘要：

雌激素在体内的重要功能由雌激素受体(ER)介导。ER是近年生殖生物学及内分泌学研究的热点之一。从ER的分子结构和功能、定位与分布、ER介导的基因表达与调控以及ER的检测与肿瘤等几个方面,对近年来ER研究的进展进行综述。

引用

页码：348 / 351

页数：4

共 6 条

[1]

Membrane association of estrogen receptor α mediates estrogen effect on MAPK activation [J].

Zhang, ZG ;

Maier, B ;

Santen, RJ ;

Song, RXD .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2002, 294 (05) :926-933

[2]

Estrogen receptor-mediated effects of tamoxifen on human endometrial cancer cells.[J].Takako Sakamoto;Hidetaka Eguchi;Yoko Omoto;Takuya Ayabe;Hiroyuki Mori;Shin-ichi Hayashi.Molecular and Cellular Endocrinology.2002, 1

[3]

Suppression by estrogen receptor β of AP-1 mediated transactivation through estrogen receptor α [J].

Maruyama, S ;

Fujimoto, N ;

Asano, K ;

Ito, A .

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2001, 78 (02) :177-184

[4]

Estrogen receptor α mediated induction of the transforming growth factor α gene by estradiol and 4-hydroxytamoxifen in MDA-MB-231 breast cancer cells [J].

Schafer, JM ;

Liu, H ;

Levenson, AS ;

Horiguchi, J ;

Chen, ZH ;

Jordan, C .

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2001, 78 (01) :41-50

[5]

Estrogen receptors: How do they control reproductive and nonreproductive functions? [J].

Muramatsu, M ;

Inoue, S .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 270 (01) :1-10

[6]

Ligand-independent recruitment of SRC-1 to estrogen receptor β through phosphorylation of activation function AF-1 [J].

Tremblay, A ;

Tremblay, GB ;

Labrie, F ;

Giguère, V .

MOLECULAR CELL, 1999, 3 (04) :513-519

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