辅刺激因子调节剂——类风湿关节炎治疗的新途径

被引:1
作者
张卓莉
董怡
机构
[1] 中国医学科学院中国协和医科大学北京协和医院风湿免疫科
关键词
辅刺激因子; 类风湿关节炎; T淋巴细胞; 阿巴西普;
D O I
暂无
中图分类号
R593.22 [类风湿性关节炎];
学科分类号
摘要
近年来研发的辅刺激因子调节剂如阿巴西普(abatacept)和LEA29Y可以调节抗原特异性T淋巴细胞的功能、有效改善类风湿关节炎患者的症状和体征。笔者对辅刺激因子调节剂的免疫学基础、动物实验以及临床研究等方面进行综述,为进一步的临床应用提供参考。
引用
收藏
页码:845 / 848
页数:4
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