糖皮质激素引发骨质疏松的机理及对策

被引：15

作者：

赵学伟

钱叶勇

机构：

[1] 中国人民解放军医院

[2] 中国人民解放军医院北京

[3] 北京

来源：

中国医院药学杂志 | 2002年 / 12期

关键词：

糖皮质激素; 骨质疏松;

D O I：

暂无

中图分类号：

R58 [内分泌腺疾病及代谢病];

学科分类号：

摘要：

目的:综述糖皮质激素(glycocorticoid,GC)引起骨丢失的主要机理及防治对策。方法:检索近10年文献,综述评价。结果:GC的主要不良反应是骨质疏松。有效的检查、预防治疗可以避免或延缓骨质疏松的发生。结论:每例患者都要测定骨矿物质密度(Bone Mineral Density,BMD)基线值及对危险因素进行全面评估。双光子X射线吸光测定法(Dual Photon X-rayAbsorptiometry,DEXA)是测定BMD的黄金标准。饮食中的不足、性腺机能减退应予以纠正,临床可选择性应用二膦酸盐、骨化三醇、降钙素等药物。

引用

页码：51 / 53

页数：3

共 14 条

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